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Why it is important to spike insulin after exercise?
Raising the blood insulin level is key to stimulating muscle protein anabolism and limiting protein degradation following exercise. While amino acid ingestion alone significantly increases muscle protein anabolism after resistance exercise, consumption of both amino acids and carbs results in much greater effects on muscle protein anabolism, indicating an interactive effect between insulin, amino acid availability and resistance exercise.
What is hydrolyzed whey protein?
Whey protein hydrolysates (i.e., pre-digested whey proteins) are produced from purified whey protein sources by heating with acid or preferably, addition of enzymes, followed by purification procedures. Hydrolysis process actually mimics our own digestive actions; thus, many experts feel it is an ideal way to process dietary protein, especially when ultra rapid absorption is important (e.g., immediatelty after exercise). Extensively hydrolyzed proteins containing mostly di- and tripeptides (chains of two and three amino acids) are absorbed more rapidly than free form amino acids and much more rapidly than intact (non-hydrolyzed) proteins.
Current evidence indicates that only di- and tripeptides are absorbed intact. Larger peptides appear to require hydrolysis before their breakdown products can be absorbed. While the starter protein and method of hydrolysis affect absorptive characteristics, the peptide-chain length is the most important variable. Protein hydrolysates produced from various sources showed increased amino acid absorption in humans when the proportion of di- and tripeptides was increased. Thus, in order to maximize absoption rate, the ideal protein hydrolysate should contain mainly tri- and tripeptides. Such a protein hydrolysate produces the most immediate hyperaminoacidemia (i.e., high levels of amino acids), and in turn the levels of essential amino acids in the blood regulate muscle protein anabolism.
A practical advantage is that one can ingest a protein hydrolysate-containing supplement immediately after exercise without getting bloated and not excessively suppressing appetite, so one can eat another meal sooner, possibly optimizing the post-exercise "anabolic window". In addition, protein hydrolysates strongly stimulate insulin secretion.
Why is leucine so important for post-exercise muscle anabolism?
The key branched-chain amino acid leucine acts as a nutrient signal to stimulate muscle protein anabolism. Leucine affect muscle protein metabolism by decreasing the rate of protein degradation most likely via increases in circulating insulin. In addition, leucine activates key molecules involved in the regulation of protein synthesis, which has been shown to occur even in the absence of an increase in circulating insulin concentrations. After exercise, recovery of muscle protein synthesis requires dietary protein or branched-chain amino acids to increase tissue levels of leucine. The important bottom line is that insulin and leucine allow skeletal muscle to coordinate protein synthesis with physiological state and dietary intake.
*A sensible diet and regular exercise are essential for achieving your weight loss goal.
The information contained herein is for informational purposes only and should not be construed as medical advice. Specific medical advice should only be obtained from a licensed health care professional. Product descriptions and general information are based on a combination of factors and sources, including customer feedback, customer reviews, manufacturer's literature, product labels, and/or opinions of the author(s). No liability is assumed by NutraQuest for any information herein.
The information contained herein is for informational purposes only and should not be construed as medical advice. Specific medical advice should only be obtained from a licensed health care professional. Product descriptions and general information are based on a combination of factors and sources, including customer feedback, customer reviews, manufacturer's literature, product labels, and/or opinions of the author(s). No liability is assumed by Bioquest for any information herein. These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
*A sensible diet and regular exercise are essential for achieving your weight loss goal.
The information contained herein is for informational purposes only and should not be construed as medical advice. Specific medical advice should only be obtained from a licensed health care professional. Product descriptions and general information are based on a combination of factors and sources, including customer feedback, customer reviews, manufacturer's literature, product labels, and/or opinions of the author(s). No liability is assumed by NutraQuest for any information herein.
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© 2010 BioQuest, Inc. A Division of NutraQuest, Inc. All Rights Reserved.
| Healthy weight management and substantial weight loss are best achieved by making lifestyle changes, such as lowering caloric intake and increasing exercise activity. Clinical evidence indicates that when used in combination with a sensible diet and exercise, the key ingredients can support your weight loss program. Consult a health care professional before beginning any weight-loss program. Read and follow all label instructions before using. Endorsers used this product in conjunction with diet and exercise and were remunerated for their appearance. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. |